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ABSTRACTS

 

Feasibility and Safety of Targeted Temperature Management During Interhospital Transport of Post–Cardiac Arrest Patients

Author: Ki Hong Kim, Choi Seul Ki, Ro Young Sun, and Shin Sang Do | |

Associate Authors:

Introduction:

Targeted temperature management (TTM) during interhospital transport (IHT) could be helpful in maintaining a patient’s target temperature or in initiating TTM early.

Objective:

To evaluate the feasibility and safety of TTM by external device cooling versus standard intensive care during IHT in patients resuscitated from cardiac arrest.

Methods:

A retrospective observational study based on the IHT registry of one dedicated critical care transport system was conducted. Adult patients resuscitated from cardiac arrest without mental recovery, contraindication for TTM, and missing information of body temperature were enrolled. Study participants were categorized as interhospital TTM or non-interhospital TTM. The primary outcome was body temperature drop during transport. Successful TTM, hypotension, or desaturation during transport were considered as secondary outcomes. Multivariable conditional logistic regression analysis was performed according to interhospital TTM after frequency matching with age, gender, and body temperature at the request hospital.

Results:

A total of 593 patients were transported from January 2016 to April 2023; 332 patients were analyzed after exclusion. Forty-four patients (13.3%) were provided interhospital TTM, and there were no significant differences of interhospital events compared to the non-interhospital TTM group. After frequency matching, 82 patients in the non-interhospital TTM group and 42 patients in the interhospital TTM group were analyzed. Significant association was found for body temperature drop during transport (aOR = 12.91, 95% CI = 5.28–31.53). No significant association was found for successful TTM, hypotension, or desaturation during IHT.

Conclusion:

TTM by external device cooling was feasible and safe during IHT. It should be considered for patients who may benefit from early and continuous TTM.